Diversity libraries · FOCUSED LIBRARIES · CUSTOM SELECTIONS
Vitas-M offers ready-to-use compound libraries for primary HTS screening, phenotypic screening, target based screening, assay development and assay validation, hit finding and lead follow-up. Choose from diversity libraries, fragment sets, focused libraries, True Baseline and Active Reference collections or ask us to prepare a selection based on your own criteria.
Please share a brief description of what you are currently working on and what you are aiming to solve. We will recommend the most relevant products from our portfolio of curated screening compound libraries to support your task.
Different discovery tasks need different compound selections. Some projects need broad diversity. Some need fragments. Some need positive or negative reference compounds. Others need a focused library around a target family, disease area or internal shortlist.
Seeds, Blossoms and Orchard libraries provide broad chemical space coverage for project starts, screening expansion, initial stage of phenotypic screening, and advanced discovery. Request them when you need a large, pre-filtered small-molecule set rather than a random catalogue slice. Seeds: 10K compounds · Blossoms: 37K compounds · Orchard: 55K compounds.
A fragment‑based drug discovery set for early hit finding and fragment screening workflows. Available as an SD file on request for review before quotation. All compounds are selected according to the Rule of 3 and have low molecular weight with one or more active binding centers.
True Baseline and Active Reference libraries are designed for assay development and experimental result validation. True Baseline / NEGMARK contains compounds with documented inactivity in PubChem BioAssay and can be used as a negative-reference set for HTS assay validation, signal-window calibration and control of false positive signals. Active Reference / POSIMARK contains compounds with reported experimental activity and can support positive-reference design, assay validation, hit identification and HTS follow-up. NEGMARK: 6,643 compounds · POSIMARK: 27,381 compounds.
For projects that need broader chemical coverage or follow-up around known actives, Vitas-M can provide diversity-oriented selections and focused analog options. These sets can support early exploration, screening expansion, hit follow-up and lead-optimization planning when a simple catalogue search is not enough.
Vitas-M focused libraries are available for multiple target families and research areas, including bacterial targets, enzymes, proteases, viral targets, ion channels, CNS-related targets, receptors, cancer-related proteins, inflammation-related proteins, immune-system proteins, macrocycles, RNA-related targets and transcription factors.
Available focused library areas include bacterial cell wall proteins, general bacterial proteins, bacterial protein synthesis inhibitors, Streptococcus, tuberculosis-related proteins, ATPases, DNA polymerases, arginase, helicases, isomerases, kinases, ligases, phosphatases, transferases, calcium channels, CNS library, cytochromes, GABA receptors, GPCR proteins, glutamate receptors, Hedgehog pathway proteins, ion channels, nuclear receptors, neurotransmitter transporters, RNAs, transcription factors, voltage-gated ion channels, caspases, cysteine proteases, proteases, serine proteases, avian influenza, coronaviral proteins, hepatitis-associated proteins, HIV-related proteins, retroviral proteins and general antiviral compounds.
If a ready Vitas-M library is not the right fit, we can prepare a specially tailored compound set based on your project criteria. You can start from desired set size, internal hit list, SMILES list, Vitas-M catalogue IDs or other chemical identifiers.
We check what can be supplied from the Vitas-M catalogue, prepare available compound options, and provide stock, sample amount, price and delivery information for quotation. Tailored selections can be used for screening, assay development, hit follow-up, lead optimization, control design or internal library expansion.
From off-the-shelf Vitas-M compounds and project criteria to a quoted set of ready to use research samples.
Start from a ready Vitas-M library, a focused target-family set, or your own project criteria. You can also provide a compound list, SMILES, Vitas-M IDs or an internal shortlist.
We check relevant compounds against the Vitas-M catalogue and available stock. The set can be based on diversity, fragments, True Baseline, Active Reference, focused libraries or your own selection rules.
You receive a reviewable compound set with catalogue IDs, structures or SD file when available, sample amounts, and any notes needed before quotation.
After confirmation, we prepare price and delivery information. Available compounds are supplied as research samples in the agreed amount and format.
Yes. We can start from a ready Vitas-M library, a focused target-family library, or your own project criteria. The final set can be prepared around your research stage, desired set size, target family, property window, internal hit list or compound identifiers.
Both. Vitas-M has a searchable catalogue of screening compounds and building blocks, but we also offer curated libraries, focused libraries, True Baseline, Active Reference, fragment sets and specially tailored selections based on customer criteria.
A diversity library is a pre-filtered small-molecule set designed to cover broad chemical space. Vitas-M diversity libraries can be used for project starts, primary screening, screening expansion and early hit finding.
True Baseline and Active Reference libraries are experimental reference sets for assay development and result validation. True Baseline / NEGMARK is based on compounds with documented inactivity in PubChem BioAssay. Active Reference / POSIMARK is based on compounds with reported experimental activity. Together, they can help test whether an assay gives reliable negative and positive signals.
Yes. Vitas-M focused libraries cover multiple target families and research areas, including bacterial targets, enzymes, proteases, viral targets, ion channels, CNS-related targets, receptors, cancer-related proteins, inflammation-related proteins, immune-system proteins, RNA-related targets and transcription factors.
Usually, we ship each order as one delivery. For large compound sets or screening panels, partial delivery can be discussed when some compounds are ready earlier than the rest.
Vitas-M supplies small-molecule research samples from 1 mg to 5 g per compound. Quantities above 5 g per compound are not supplied. Available sample amounts are confirmed during quotation.
Yes. SD files for selected Vitas-M libraries or proposed compound sets can be requested for review before quotation, when available.
Share your target family, project stage, desired set size or selection criteria. We will check Vitas-M libraries and catalogue compounds, then reply with available options, price and delivery.
Have a large compound list already? We can check that too.
